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  1. Systemic sclerosis prevalence and mortality in Sydney 1974-88.

    Article - En anglais

    Background 

    Systemic sclerosis prevalence and mortality estimates have demonstrated wide variability.

    The sole Australian study published to date demonstrated high prevalence rates when compared to overseas estimates.

    The prevalence and mortality findings reported in this paper derive from a larger study which addressed the distribution and determinants of systemic sclerosis within Sydney.

    Aims 

    To determine systemic sclerosis prevalence and mortality rates within Sydney over 15 years, 1974-88.

    Methods 

    Cases were ascertained from multiple sources including death certificates, hospitals, physicians, vascular surgeons'and dermatologists'private practices, a systemic sclerosis self-help group and private medical laboratories.

    Results 

    Overall, 715 cases were identified.

    Females comprised 77% (95% CI : 74-80) of cases.

    Disease of the limited subtype accounted for 79% (95% CI : 76-82) of all systemic sclerosis, being relatively more frequent in living than deceased cases, and in females than males.

    Crude prevalence estimates appeared to rise between 1975 (4.52/100,000 95% CI : 3.75-5.29/100,000) and 1988 (8.62/100,000 95% CI : 7.64-9.60/100,000) as did estimates of diffuse disease.

    However, diffuse disease prevalence, when expressed as a proportion of total disease prevalence, showed no significant temporal change.

    Although crude mortality rates also showed apparent temporal increases (0.24/100,000 in 1975 to 0. (...)

    Mots-clés Pascal : Sclérodermie, Disséminé, Prévalence, Mortalité, Epidémiologie, Homme, Australie, Océanie, Peau pathologie, Tissu conjonctif pathologie, Maladie système, Maladie autoimmune, Immunopathologie

    Mots-clés Pascal anglais : Scleroderma, Disseminated, Prevalence, Mortality, Epidemiology, Human, Australia, Oceania, Skin disease, Connective tissue disease, Systemic disease, Autoimmune disease, Immunopathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0211091

    Code Inist : 002B07. Création : 16/11/1999.