Palindromic rheumatism is characterized by attacks of acute arthritis of short duration.
In the long term, a substantial proportion of patients will develop rheumatoid arthritis (RA) or other connective tissue diseases, but the determinants of subsequent chronic disease have not been adequately established.
We identify clinical prognostic factors for the development of RA and other connective tissue diseases in patients with palindromic rheumatism in a retrospective cohort study.
The medical records of 4900 patients with arthritis referred from 1986 to 1996 to 3 rheumatologists at an academic center were reviewed.
One hundred sixty patients were diagnosed as having palindromic rheumatism.
After review. 127 complied with diagnostic criteria for palindromic rheumatism.
Disease duration was estimated as time of first attack until the last consultation, or the development of RA or other connective tissue disease.
Survival analysis including Cox regression was used to identify clinical variables associated with the risk of developing RA or other connective tissue disease, adjusting for varying disease duration.
Sixty-five percent of the patients were female.
Age at onset was 40 ± 12 years.
Mean disease duration was 6 ± 6 years, and mean followup by the rheumatologists was 40 ± 45 months.
Joints more frequently affected were wrist, knee, and metacarpophalangeal. (...)
Mots-clés Pascal : Rhumatisme palindromique, Evolutivité, Complication, Tissu conjonctif pathologie, Facteur prédictif, Facteur rhumatoïde, Polyarthrite rhumatoïde, Pronostic, Homme, Epidémiologie, Symptomatologie, Aigu, Chronique, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire, Peau pathologie, Immunopathologie, Maladie autoimmune
Mots-clés Pascal anglais : Palindromic rheumatism of Hench, Evolutivity, Complication, Connective tissue disease, Predictive factor, Rheumatoid factor, Rheumatoid arthritis, Prognosis, Human, Epidemiology, Symptomatology, Acute, Chronic, Diseases of the osteoarticular system, Inflammatory joint disease, Skin disease, Immunopathology, Autoimmune disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0207213
Code Inist : 002B15D. Création : 16/11/1999.