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  1. Nonylphenol and estrogenic activity in aquatic environmental samples.

    Article - En anglais

    We surveyed a series of surface waters and sewage treatment plants in Flanders (north of Belgium) for the presence of estrogenic activity and a xeno-estrogenic compound para-nonylphenol (NP), respectively.

    The surface waters of rural origin, used for drinking water production, were free of significant levels of estrogenic activity and NP (<1 mug/L).

    Domestic sewage, after proper treatment, appeared to be no major source of this chemical.

    Yet, in some industrial effluents and surface waters of highly industrialized regions, NP and/or estrogenic activity was prominent, that is,<1 to 122 mug NP/L and 11 to 42 mug NP/L, respectively.

    This is because of the ongoing use of NP polyethoxylates in industry.

    The response of the recombinant yeast estrogen assay to the environmental samples tested was not consistent with the detected concentrations of NP.

    Standard addition of a natural estrogen, 17bêta-estradiol, generated no or a reduced response compared to the standard curve concentration.

    Application of humic acids to standard series of NP and 17bêta-estradiol resulted in a dose-dependent decrease of the estrogenic response.

    It appears that this bioassay is subject to considerable interferences due to the complexity of environmental samples.

    Parallel implementation of extensive chemical screening for xenobiotics and use of the bioassay are needed for adequate assessment of the potential estrogenic hazard to avoid false negative evaluations.

    Mots-clés Pascal : Belgique, Europe, Pollution eau, Eau surface, Eau usée urbaine, Eau usée industrielle, Qualité eau, Contrôle, Analyse chimique, Analyse quantitative, Essai biologique, Oestrogène, Xénobiotique, 17bêta-Oestradiol, Agent surface non ionique, Ethylène oxyde polymère, Ethylène oxyde polymère nonylphényle, Perturbateur endocrinien

    Mots-clés Pascal anglais : Belgium, Europe, Water pollution, Surface water, Urban waste water, Industrial waste water, Water quality, Check, Chemical analysis, Quantitative analysis, Bioassay, Estrogen, Xenobiotic, 17bêta-Estradiol, Non ionic surfactant, Ethylene oxide polymer, Endocrine disruptor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0203414

    Code Inist : 001D16A04C. Création : 16/11/1999.