In our previous work, we reported the first systematic, island-wide, serologic survey for schistosomiasis in Puerto Rico in 40 years.
In that study, approximately 3,000 serum samples from the 76 municipalities comprising the island of Puerto Rico were tested for the detection of antibodies to S. mansoni microsomal antigens by the Falcon assay screening test-enzyme-linked immunosorbent assay (FAST-ELISA) and those positive were confirmed by an enzyme-linked immunoelectrotransfer blot (EITB).
The highest EITB positivity was found in 17 municipalities, which comprised 48% of all seropositive samples.
An additional finding was that 10% of the 215 EITB-positive samples were from individuals 25 years or younger and were for the most part of residents from the high seroprevalence areas.
Thus, for this study we focused on 766 individuals 25 years of age or younger (45.5% males and 54.4% females), two-thirds of which were from 10 municipalities with the highest EITB seropositivity, and one-third from the 10 municipalities with the lowest EITB seropositivity found in our previous study.
Of all samples, the results showed an overall FAST-ELISA positivity of 11.6%, with males similar to females (12.6 versus 10.7%, respectively).
Confirmation by EITB was only 1.8%, with a males three-fold higher than females (3% versus 0.7%). When seropositivity was measured by age in five-year increments, a clear age-specific decrease in seropositivity was observed.
Thus, by FAST-ELISA, 16. (...)
Mots-clés Pascal : Schistosomiase, Trématodose, Helminthiase, Parasitose, Infection, Schistosoma mansoni, Trematoda, Plathelmintha, Helmintha, Invertebrata, Surveillance, Sérologie, Prévalence, Porto Rico, Antilles, Amérique Centrale, Amérique, Homme
Mots-clés Pascal anglais : Schistosomiasis, Trematode disease, Helminthiasis, Parasitosis, Infection, Schistosoma mansoni, Trematoda, Plathelmintha, Helmintha, Invertebrata, Surveillance, Serology, Prevalence, Puerto Rico, West Indies, Central America, America, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0200257
Code Inist : 002B05E03C1. Création : 16/11/1999.