Objectives This study describes the magnetic resonance findings of benign and malignant pleural diseases in asbestos-exposed subjects.
Methods Thirty patients with a history of asbestos exposure and pleural lesions in chest X-rays and computed tomography scans were examined with a 0.5-and a 1.5-T magnetic resonance unit.
The examination protocol included cardiac-gated proton density and T2-weighted images, unenhanced and enhanced (Gd-DTPA ; 0. 1 mmol/kg) T1-weighted images in the axial plane and sometimes in another orthogonal plane (sagittal or coronal or both).
All the magnetic resonance images were reviewed by 3 experienced observers, who visually evaluated morphologic features, signal intensity, and contrast enhancement of pleural lesions.
The diagnosis was established by means of percutaneous biopsy, thoracotomy, and combined clinical and radiological follow-up for at least 3 years.
Results Eighteen patients affected with multiple pleural plaques showed low signal intensity on both unenhanced and enhanced T1-weighted and proton density and T2-weighted images.
In 2 of these patients an acute pleural effusion was observed.
All the malignant lesions (I mesotheliomas) and a solitary benign pleural plaque revealed high signal intensity on the proton density and T2-weighted images and inhomogeneous contrast enhancement in the postcontrast T1-weighted images. (...)
Mots-clés Pascal : Exposition professionnelle, Amiante, Industrie, Mésothéliome bénin, Plèvre, Mésothéliome malin, Méthode étude, Aide diagnostic, Résonance magnétique, Imagerie médicale, Homme, Evaluation, Sensibilité, Spécificité, Médecine travail, Appareil respiratoire pathologie, Plèvre pathologie, Tumeur bénigne, Tumeur maligne
Mots-clés Pascal anglais : Occupational exposure, Asbestos, Industry, Benign mesothelioma, Pleura, Malignant mesothelioma, Investigation method, Diagnostic aid, Magnetic resonance, Medical imagery, Human, Evaluation, Sensitivity, Specificity, Occupational medicine, Respiratory disease, Pleural disease, Benign neoplasm, Malignant tumor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0198242
Code Inist : 002B24A02. Création : 16/11/1999.