A recent study found high rates of leukemia and related disorders among teachers.
This finding may be related to exposure to childhood infections.
Therefore, epidemiologic studies on the risk of lymphatic and hematopoietic cancer among teachers were systematically reviewed.
Altogether 26 relevant investigations were identified, most from ad hoc publications rather than from scientific journals.
Elevated risks of leukemia, lymphoma, and multiple myeloma were found in studies using proportional mortality or mortality odds ratios as outcome measures.
However, these observations may reflect low overall mortality and do not necessarily indicate high death rates from the cancers of interest.
In studies deriving standardized mortality or incidence ratios, the risk estimates were generally lower.
The most striking finding was for non-Hodgkin's lymphoma (approximate summary relative risk 1.36,95% confidence interval 1.13-1.62), but it was likely to have been exaggerated by publication bias.
In conclusion, no compelling epidemiologic evidence exists for a hazard of leukemia or related diseases among teachers.
Mots-clés Pascal : Médecine travail, Enseignant, Homme, Hodgkin maladie, Facteur risque, Myélome, Evaluation, Rapport standardisé mortalité, Biais méthodologique, Article synthèse, Hémopathie maligne, Lymphoprolifératif syndrome, Lymphome, Immunopathologie, Immunoglobulinopathie
Mots-clés Pascal anglais : Occupational medicine, Teacher, Human, Hodgkin disease, Risk factor, Myeloma, Evaluation, Standardized mortality ratio, Methodological bias, Review, Malignant hemopathy, Lymphoproliferative syndrome, Lymphoma, Immunopathology, Immunoglobulinopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0198153
Code Inist : 002B19B. Création : 16/11/1999.