Active infection with Helicobacter pylori in healthy couples.
The mode of spread of Helicobacter pylori infection is subject to ongoing debate.
Recent studies among patients with gastrointestinal disorders suggest a potential role of conjugal transmission.
In this study, the clustering of H. pylori infection was assessed among 110 employees of a health insurance company and their partners.
Active infection with H. pylor was measured by the 13C-urea breath test.
Information on potential confounders was collected by a standardized questionnaire.
Overall, 16 employees (14.5%) and 24 partners (21.8%) were infected.
While only 7% (6/86) of employees with an uninfected partner were infected, this applied to 42% (10/24) of employees with an infected partner.
A very strong relation between partners'infection status persisted after control for age and other potential confounders (adjusted odds ratio, 7.0 ; 95% confidence interval, 1.8-26.7).
Furthermore, the risk of infection increased with the number of years lived with an infected partner.
These results support the hypothesis of a major role of spouse-to-spouse transmission of H. pylor infection.
Mots-clés Pascal : Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Bactériose, Infection, Homme, Couple, Transmission homme homme, Conjoint, Epidémiologie, Estomac pathologie, Appareil digestif pathologie
Mots-clés Pascal anglais : Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Bacteriosis, Infection, Human, Couple, Transmission from man to man, Spouse, Epidemiology, Gastric disease, Digestive diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0195343
Code Inist : 002B05B02F. Création : 16/11/1999.