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  1. Fulltext. HIV-1 incidence among opiate users in northern Thailand.

    Article - En anglais


    The incidence of human immunodeficiency virus type 1 (HIV-1) infection among opiate users was determined in a retrospective cohort of 436 patients with multiple admissions to the only inpatient drug treatment program in northern Thailand between October 1993 and September 1995.

    During 323.4 person-years of follow-up, 60 patients presenting for detoxification acquired HIV-1 infection, for a crude incidence rate of 18.6 per 100 person-years (95% confidence interval 14.4-23.9).

    All seroconverters were male.

    HIV-1 incidence varied by the current route of drug administration : 31.3 per 100 person-years for injectors and 2.8 per 100 person-years for noninjectors (smoking and ingestion).

    Significant differences were found by ethnicity : HIV-1 incidence was 29.3 per 100 person-years for Thai lowlanders and 8.5 per 100 person-years for hilltribes.

    Multivariate relative risk estimates showed that injecting opiates (vs. use by other routes), being unmarried, being under age 40 years, being a Thai lowlander, having a primary and secondary education, and being employed in the business sector were each independently associated with human immunodeficiency virus seroconversion.

    This HIV-1 incidence rate is double that reported for Bangkok and suggests that prevention and control programs for drug users need to be expanded throughout Thailand. (...)

    Mots-clés Pascal : SIDA, Virose, Infection, Dépistage, Homme, Toxicomanie, Drogue illicite, Opiacés, Ethnie, Thaïlande, Asie, Epidémiologie, Incidence, Etude cohorte, Immunopathologie, Immunodéficit

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Medical screening, Human, Drug addiction, Illicit drug, Opiates, Ethnic group, Thailand, Asia, Epidemiology, Incidence, Cohort study, Immunopathology, Immune deficiency

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0192653

    Code Inist : 002B05C02D. Création : 16/11/1999.