Alcoholic beverages are known to have strong antibacterial activity.
It is unclear, however, to what degree their consumption affects colonization of the human stomach with the bacterium Helicobacter pylori, a risk factor of various chronic diseases.
The authors assessed the relation between alcohol consumption and active infection with H. pylori in a cross-sectional study among employees of a health insurance company and their household members (n=425) in southern Germany.
Quantitative information on alcohol consumption by beverage type and other factors that were known or suspected to be related to infection status was collected by a standardized questionnaire, and active infection was measured by the 13C-urea breath test.
After control for confounding factors, there was a monotonic inverse graded relation between alcohol consumption and H. pylori infection (p for trend=0.017).
The odds ratio of infection among subjects who consumed more than 75 g of alcohol per week compared with subjects who did not drink alcohol was 0.31 (95 percent confidence interval 0.12-0.81).
The inverse relation with H. pylori infection was stronger for alcohol consumed in the form of wine than for alcohol from beer.
Notwithstanding its cross-sectional design, this study seems to support the hypothesis that alcohol consumption, particularly wine consumption, may reduce the odds of active infection with H. pylori.
Mots-clés Pascal : Gastrite, Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Homme, Allemagne, Europe, Epidémiologie, Prévalence, Consommation alimentaire, Boisson alcoolisée, Vin, Bière, Relation, Inverse, Etude transversale, Appareil digestif pathologie, Estomac pathologie
Mots-clés Pascal anglais : Gastritis, Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Human, Germany, Europe, Epidemiology, Prevalence, Food intake, Alcoholic beverage, Wine, Beer, Relation, Inverse, Cross sectional study, Digestive diseases, Gastric disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0192492
Code Inist : 002B05B02F. Création : 16/11/1999.