Several epidemiologic investigations have suggested that weight loss is associated with increased mortality risk but have not examined whether the weight loss was intentional or unintentional.
The authors examined whether the association between weight loss and mortality differs by whether the weight loss was intentional or unintentional as part of the lowa Women's Health Study, a prospective cohort study of health risk factors in postmenopausal women.
Women aged 55-69 years completed questions about intentional and unintentional weight losses since age 18 years via mail survey in 1992 and were followed through 1995.
One or more intentional weight loss episodes of 20 or more pounds (>=9.1 kg) during adulthood was not significantly associated with higher total or cardiovascular disease mortality risk compared with never losing >=20 pounds.
One or more unintentional weight loss episodes of 20 or more pounds was associated with a 26-57% higher total mortality risk and a 51-114% higher cardiovascular disease mortality risk, compared with never losing 20 or more pounds.
Associations between unintentional weight loss and increased mortality risk were confined mostly to women with prevalent disease, hypertension, or diabetes.
Patterns of association did not vary by overweight status. (...)
Mots-clés Pascal : Obésité, Personne âgée, Homme, Femelle, Ménopause, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Perte poids, Volontaire, Evolution, Mortalité, Etude cohorte, Questionnaire, Evaluation, Etat nutritionnel, Trouble nutrition
Mots-clés Pascal anglais : Obesity, Elderly, Human, Female, Menopause, United States, North America, America, Epidemiology, Weight loss, Volunteer, Evolution, Mortality, Cohort study, Questionnaire, Evaluation, Nutritional status, Nutrition disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0191107
Code Inist : 002B22B. Création : 16/11/1999.