Neonatal tetanus : A continuing challenge in the southeast of Turkey : Risk, factors, clinical features and prognostic factors.
Neonatal tetanus (NT) still causes significant mortality in developing countries, although in 1989 WHO adopted the goal of eliminating the disease by 1995-2000.
To characterize the regional characteristics, clinical charts of 55 neonates (42 males and 13 females) admitted to the Pediatric Infectious Diseases Ward of Dicle University Hospital.
Diyarbakir, Turkey with the diagnosis of NT from 1991 to 1997 were reviewed.
Mean age at admittance was 8.9 ± 4.3 days with a range of 3-25 days.
Mean period for the appearance of first symptoms was 5.8 days ranging between 1 and 21 days.
Mean birth weight of the patients was 3369 ± 560 g. All patients were from rural areas and were delivered at home by untrained traditional birth attendants with no prior antenatal healthcare services.
Razor blade (55%), scissors (27%), and knife (18%) were the instruments used to cut the cord in non-hygienic conditions.
No mothers had prior vaccination with tetanus toxoid during their pregnancy.
Spasticity (76%), lack of sucking (71%), trismus (60%), fever (49%), omphalitis (44%), irritability (24%), risus sardonicus (22%), and opithotonus (15%) were the most common presenting signs and symptoms.
Age at admission<7.5 days and symptoms of onset<4.9 days, risus sardonicus and opisthotonus were associated with fatal outcome.
All patients were treated with human tetanus immunglobulin or equine tetanus antitoxin where available, antibiotic therapy by penicillin G (...)
Mots-clés Pascal : Tétanos, Bactériose, Infection, Néonatal, Nouveau né, Homme, Turquie, Asie, Epidémiologie, Prévalence, Facteur risque, Symptomatologie, Evolution, Mortalité, Pronostic, Recommandation, Milieu rural, Nouveau né pathologie
Mots-clés Pascal anglais : Tetanus, Bacteriosis, Infection, Neonatal, Newborn, Human, Turkey, Asia, Epidemiology, Prevalence, Risk factor, Symptomatology, Evolution, Mortality, Prognosis, Recommendation, Rural environment, Newborn diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0190606
Code Inist : 002B05B02I. Création : 16/11/1999.