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  1. Comparison of lung-function reference values.

    Article - En anglais


    Lung-function reference values play an important role in medical surveillance examinations of occupational and environmental respiratory diseases, in stipulation of preventive measures, in initiation of therapeutic measures, and in granting of benefits to which individuals with lung injuries or occupational lung diseases are entitled (e.g., bronchial asthma, pneumoconiosis, or farmer's lung disease).

    Prediction equations most widely used are based on studies performed more than 20 years ago and may not represent the findings obtained in today's population.


    We recorded case histories and lung function values of 139 healthy subjects (spirometric and plethysmographic data, TLCO) and computed the differences of measured values minus predicted ones as recommended by different authors.


    The means of these differences can be seen as shifts in our group versus the theoretical (predicted) values of various authors.

    These shifts, the standardized mean values of residuals, and their probability as determined under the assumptions of the respective regression model and the number of subjects below the threshold limits are given.

    FVC, FEV1, and FEV1% FVC show mostly good agreement with the recommendations by Crapo et al., Roca et al., Glindmeyer et al., Brändli et al., and Berger et al.

    Our IVC and FVC values do not differ significantly from each other. (...)

    Mots-clés Pascal : Médecine travail, Méthodologie, Fonction respiratoire, Modèle prévision, Etude comparative, Biais méthodologique, Evaluation performance, Homme, Individu sain, Pléthysmographie, Spirométrie, Surveillance, Valeur prédictive

    Mots-clés Pascal anglais : Occupational medicine, Methodology, Lung function, Forecast model, Comparative study, Methodological bias, Performance evaluation, Human, Healthy subject, Plethysmography, Spirometry, Surveillance, Predictive value

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0187979

    Code Inist : 002B30A01C. Création : 16/11/1999.