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  1. Suicide attempts in major affective disorder patients with comorbid substance use disorders.

    Article, Communication - En anglais

    Effects of Medical Interventions on Suicidal Behaviors. Symposium. Miami, FL, USA, 1998/02/26.


    The widely accepted impression that substance abuse and dependence are associated with increased suicidal risk was evaluated by literature review and with new data.


    Previous research on this association was reviewed, and clinical data on suicide attempts and substance use in 504 mood disorder patients hospitalized in 4 psychiatric units in Sardinia affiliated with the Italian mental health system were analyzed.


    The literature supports associations of alcohol and drug use comorbidity with major affective disorders, and of some substances (polyabuse, alcohol, heroin, cocaine, and even tobacco, but perhaps not marijuana or hallucinogens) with suicidal behavior.

    Our new findings generally supported these 2-way associations.

    Suicidal risks were similar in hospitalized men and women but were associated with bipolar II, bipolar I (mainly mixed), and unipolar depressive disorders as well as substance abuse, with little effect of type of agent.

    Substance abuse was more common in nonmixed bipolar disorders, men, and age below 30.


    The tendency for bipolar I, mainly nonmixed patients, to have a relatively high risk of substance abuse and low risk of suicide attempts indicates that mainly depressive or dysphoric (bipolar II, nonbipolar, and bipolar I, mainly mixed) mood disorders may be especially lethal. (...)

    Mots-clés Pascal : Etat dépressif, Association morbide, Toxicomanie, Alcoolisme, Facteur risque, Suicide, Prévalence, Epidémiologie, Santé mentale, Homme, Trouble humeur

    Mots-clés Pascal anglais : Depression, Concomitant disease, Drug addiction, Alcoholism, Risk factor, Suicide, Prevalence, Epidemiology, Mental health, Human, Mood disorder

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0187415

    Code Inist : 002B18C07A. Création : 16/11/1999.