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  1. Intracerebral hemorrhage in young people : Analysis of risk factors, location, causes, and prognosis.

    Article - En anglais

    Background and Purpose-The frequency of intracerebral hemorrhages (ICHs) in people aged <=40 years has been poorly studied.

    We investigated the incidence, causes, locations, and prognosis of ICH in young patients.

    Methods-We evaluated all consecutive patients with neuroimaging evidence or pathological confirmation of symptomatic ICH.

    We excluded patients with primary subarachnoid or traumatic hemorrhage, past evidence of vascular malformation, or brain tumor.

    We analyzed the risk factors, number, locations, and causes of ICH, and final outcome measured by the modified Glasgow Outcome Scale.


    We retrospectively evaluated 200 patients (mean age, 27 years ; range, 15 to 40 years).

    The most frequent risk factors were tobacco use (20%), hypocholesterolemia (35%), hypertension, (13%), and alcohol use (10%). The locations of ICH were lobar (55%), basal ganglia/internal capsule (22%), and others (24%). The most common causes of ICH were vascular malformations (49%), including cavernous angioma, and hypertension (11%). Cryptogenic ICH was considered in 15%. Other causes included cerebral venous thrombosis (5%) and sympathomimetic drug use (4%). The majority of patients with ICH that resulted from hypertension were aged>31 years (odds ratio, 3.48), and those with ICH that resulted from arteriovenous malformations were aged<20 years (odds ratio, 2.80).

    The final outcome was considered favorable in 60%. (...)

    Mots-clés Pascal : Hémorragie cérébrale, Localisation, Mortalité, Mexique, Amérique Centrale, Amérique, Efficacité traitement, Incidence, Epidémiologie, Facteur risque, Adulte jeune, Homme, Pronostic, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Cérébrovasculaire pathologie, Appareil circulatoire pathologie, Vaisseau sanguin pathologie

    Mots-clés Pascal anglais : Cerebral hemorrhage, Localization, Mortality, Mexico, Central America, America, Treatment efficiency, Incidence, Epidemiology, Risk factor, Young adult, Human, Prognosis, Nervous system diseases, Central nervous system disease, Cerebral disorder, Cerebrovascular disease, Cardiovascular disease, Vascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0180430

    Code Inist : 002B17C. Création : 16/11/1999.