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  1. Effect of hospital volume on in-hospital mortality with pancreaticoduodenectomy.

    Article - En anglais


    Reports of better results at national referral centers than at low-volume community hospitals have prompted calls for regionalizing pancreaticoduodenectomy (the Whipple procedure).

    We examined the relationship between hospital volume and mortality with this procedure across all US hospitals.


    Using information from the Medicare claims database, we performed a national cohort study of 7229 Medicare patients more than 65 years old undergoing pancreaticoduodenectomy between 1992 and 1995.

    We divided the study population into approximate quartiles according to the hospital's average annual volume of pancreaticoduodenectomies in Medicare patients : very low (<1/y), low (I-2/y), medium (2-5/y), and high (5+/y).

    Using multivariate logistic regression to account for potentially confounding patient characteristics, we examined the association between institutional volume and in-hospital mortality, our primary outcome measure.


    More than 50% of Medicare patients undergoing pancreaticoduodenectomy received care at hospitals performing fewer than 2 such procedures per year In-hospital mortality rates at these low-and very-low-volume hospitals were 3-to 4-fold higher than at high-volume hospitals (12% and 16%, respectively, vs 4%, P<. 001).

    Within the high-volume quartile, the 10 hospitals with the nation's highest volumes had lower mortality rates than the remaining high-volume centers (2. 1% vs 6.2%, P<. 01). (...)

    Mots-clés Pascal : Duodénopancréatectomie, Etude cohorte, Facteur risque, Mortalité, Procédure, Base donnée, Hôpital, Evaluation, Etats Unis, Amérique du Nord, Amérique, Analyse statistique, Homme, Duodénum, Pancréas, Chirurgie

    Mots-clés Pascal anglais : Pancreatoduodenectomy, Cohort study, Risk factor, Mortality, Procedure, Database, Hospital, Evaluation, United States, North America, America, Statistical analysis, Human, Duodenum, Pancreas, Surgery

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0172557

    Code Inist : 002B25G03. Création : 16/11/1999.