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  1. Fulltext. Role of schools in the transmission of measles in rural senegal : Implications for measles control in developing countries. Commentary. Authors'reply.

    Article - En anglais


    Patterns of measles transmission at school and at home were studied in 1995 in a rural area of Senegal with a high level of vaccination coverage.

    Among 209 case children with a median age of 8 years, there were no deaths, although the case fatality ratio has previously been 6-7% in this area.

    Forty percent of the case children had been vaccinated against measles ; the proportion of vaccinated children was higher among secondary cases (47%) than among index cases (33%) (prevalence ratio=1.36,95% confidence interval (Cl) 1.04-1.76).

    Vaccinated index cases may have been less infectious than unvaccinated index cases, since they produced fewer clinical cases among exposed children (relative risk=0.55,95% Cl 0.29-1.04).

    The secondary attack rate was lower in the schools than in the homes (relative risk=0.31,95% Cl 0.20-0.49).

    The school outbreaks were protracted, with 4-5 generations of cases being seen in the two larger schools.

    Vaccine efficacy was found to be 57% (95% Cl - 23 to 85) in the schools and 74% (95% Cl 62-82) in the residential compounds.

    Measles infection resulted in a mean of 3.8 days of absenteeism per case, though this did not appear to have an impact on the children's grades.

    Among the index cases, 56% of children were probably infected by neighbors in the community, and 7% were probably infected at health centers, 13% outside the community, and 24% in one of the three schools which had outbreaks during the epidemic. (...)

    Mots-clés Pascal : Rougeole, Virose, Infection, Sénégal, Afrique, Enfant, Homme, Age scolaire, Transmission homme homme, Milieu scolaire, Milieu rural, Prévalence, Prévention, Vaccination, Surveillance sanitaire

    Mots-clés Pascal anglais : Measles, Viral disease, Infection, Senegal, Africa, Child, Human, School age, Transmission from man to man, School environment, Rural environment, Prevalence, Prevention, Vaccination, Sanitary surveillance

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0167931

    Code Inist : 002B05C02B. Création : 16/11/1999.