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  1. Ethics of randomized clinical trials and the'ALARA'approach.

    Article - En anglais

    A balanced discussion on the ethics of randomized clinical trials should not he based on a single ethical aspect such as respect for the patient's autonomy.

    Rather, the analysis should consider the four ethical principles-respect for autonomy, non-maleficence. beneficence, and justice-as applicable to all groups of persons concerned.

    We present the ethical benefits and costs of the present practice of randomized clinical trials for four groups : patients involved in clinical trials, patients not involved in trials, participating physicians and society.

    The ALARA (As Low As Reasonably Achievable) approach is then introduced and practical measures to achieve a positiv e balance between ethical benefits and costs of randomized trials are proposed.

    Mots-clés Pascal : Essai clinique, Randomisation, Ethique, Analyse avantage coût

    Mots-clés Pascal anglais : Clinical trial, Randomization, Ethics, Cost benefit analysis

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0160051

    Code Inist : 002B30A09. Création : 16/11/1999.