Targeted hepatitis C lookback : Quebec, Canada.
Since March 1990, all blood donations in Canada are screened for antibodies to hepatitis C virus (HCV).
Because HCV may cause chronic asymptomatic hepatitis, in February 1995, the Canadian Red Cross began targeted HCV lookback studies.
STUDY DESIGN AND METHODS
From March 1990 to March 1997, the Quebec Center of the Canadian Red Cross collected 1,750,846 donations, and there were 561 anti-HCV-positive repeat donors, from whom 3,196 blood components had been issued to the hospitals.
Hospital blood bank directors were asked to test recipients and return results to the Quebec Center.
One hundred nine hospitals were surveyed to determine methods and resources involved in lookback.
The transfusion medicine service at the Royal Victoria Hospital (RVH) developed a standard operating procedure for performing lookbacks and analyzed the costs and outcomes of lookbacks.
As of April 1998, information has been received on 2329 (73%) of components ; 1020 patients had died of unrelated causes, 590 were untraceable, and 353 were tested.
Of those tested, 215 (61%) were anti-HCV positive ; their average age was 47, and at least 53 percent were already aware of their HCV status.
Few hospitals had received any additional resources to perform lookbacks. (...)
Mots-clés Pascal : Transfusion, Hépatite virale C, Virose, Infection, Virus hépatite C, Hepacivirus, Flaviviridae, Virus, Identification, Morbidité, Canada, Amérique du Nord, Amérique, Rétrospective, Méthodologie, Epidémiologie, Complication, Economie santé, Homme, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Transfusion, Viral hepatitis C, Viral disease, Infection, Hepatitis C virus, Hepacivirus, Flaviviridae, Virus, Identification, Morbidity, Canada, North America, America, Retrospective, Methodology, Epidemiology, Complication, Health economy, Human, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0153469
Code Inist : 002B27D01. Création : 16/11/1999.