Background A short interval between pregnancies has been associated with adverse perinatal outcomes.
Whether that association is due to confounding by other risk factors, such as maternal age, socioeconomic status, and reproductive history, is unknown.
Methods We evaluated the interpregnancy interval in relation to low birth weight, preterm birth, and small size for gestational age by analyzing data from the birth certificates of 173,205 singleton infants born alive to multiparous mothers in Utah from 1989 to 1996.
Results Infants conceived 18 to 23 months after a previous live birth had the lowest risks of adverse perinatal outcomes ; shorter and longer interpregnancy intervals were associated with higher risks.
These associations persisted when the data were stratified according to and controlled for 16 biologic, sociodemographic, and behavioral risk factors.
As compared with infants conceived 18 to 23 months after a live birth, infants conceived less than 6 months after a live birth had odds ratios of 1.4 (95 percent confidence interval, 1.3 to 1.6) for low birth weight, 1.4 (95 percent confidence interval, 1.3 to 1.5) for preterm birth, and 1.3 (95 percent confidence interval, 1.2 to 1.4) for small size for gestational age ; infants conceived 120 months or more after a live birth had odds ratios of 2.0 (95 percent confidence interval, 1.7 to 2.4), 1.5 (95 percent confidence interval, 1.3 to 1.7), and 1.8 (95 percent confidence interval, 1.6 to 2. (...)
Mots-clés Pascal : Gestation, Evaluation, Intervalle temps, Périnatal, Facteur risque, Prévalence, Femelle, Homme, Appareil génital femelle pathologie, Prévention
Mots-clés Pascal anglais : Pregnancy, Evaluation, Time interval, Perinatal, Risk factor, Prevalence, Female, Human, Female genital diseases, Prevention
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0152395
Code Inist : 002B20F01. Création : 16/11/1999.