Background Tuberculosis (TB) rates remain high in regions of Southern Mexico despite the existence of a National Tuberculosis Program.
Understanding TB epidemiology in such settings would assist in the design of improved TB control and highlight the challenges confronting TB control in developing countries.
Methods We conducted a retrospective review of treatment control cards from 1991 to 1994 in five municipalities in a semiurban region of Southern Mexico.
Results The relatively high rate of TB observed, 42.6 per 100 000 inhabitants, did not change significantly during the study period.
Cure rates among new cases were 79% and significantly lower among retreatment cases (62%). Directly observed therapy (DOT) was administered to 84% of patients.
Approximately one-half of the retreatment cases who were not cured were compliant with therapy, suggesting that drug resistance contributed to these poor results.
Of particular concern was a core group of 16 patients who had received at least three treatments.
Conclusions This region of Mexico has persistently high TB rates despite a DOT-based TB control programme which achieves an overall cure rate of 77%. There exist many retreatment cases for whom cure rates are significantly lower.
These cases may serve as a core group for the dissemination of drug resistant TB. (...)
Mots-clés Pascal : Tuberculose, Mycobactériose, Bactériose, Infection, Epidémiologie, Prévalence, Prévention, Homme, Mexique, Amérique Centrale, Amérique, Zone urbaine
Mots-clés Pascal anglais : Tuberculosis, Mycobacterial infection, Bacteriosis, Infection, Epidemiology, Prevalence, Prevention, Human, Mexico, Central America, America, Urban area
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0147621
Code Inist : 002B05B02O. Création : 16/11/1999.