Investigation of under-ascertainment in epidemiological studies based in general practice.
Background One of the aims of the Study of Infectious Intestinal Disease (IID) in England is to estimate the incidence of IID presenting to general practice.
This sub-study aims to estimate and correct the degree of under-ascertainment in the national study.
Methods Cases of presumed IID which presented to general practice in the national study had been ascertained by their GP.
In 26 general practices, cases with computerized diagnoses suggestive of IID were identified retrospectively.
Cases which fulfilled the case definition of IID and should have been ascertained to the coordinating centre but were not, represented the under-ascertainement.
Logistic regression modelling was used to identify independent factors which influenced underascertainment.
Results The records of 2021 patients were examined, 1514 were eligible and should have been ascertained but only 974 (64%) were.
There was variation in ascertainment between the practices 30% to 93%). Patient-related factors independently associated with ascertainment were : i) vomiting only as opposed to diarrhoea with and without vomiting (OR 0.37) and ii) consultation in the surgery as opposed to at home (OR 2.18).
Practice-related factors independently associated with ascertainment were : i) participation in the enumeration study component (OR 1.78), ii) a larger number of partners (OR 0.3 for 7-8 partners) ; iii) rural location (OR 2.27) and iv) previous research experience (OR 1.92). (...)
Mots-clés Pascal : Infection, Intestin pathologie, Incidence, Médecine générale, Validité, Epidémiologie, Méthodologie, Enregistrement donnée, Evaluation, Homme, Angleterre, Grande Bretagne, Royaume Uni, Europe, Appareil digestif pathologie
Mots-clés Pascal anglais : Infection, Intestinal disease, Incidence, Internal medicine, Validity, Epidemiology, Methodology, Data logging, Evaluation, Human, England, Great Britain, United Kingdom, Europe, Digestive diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0147607
Code Inist : 002B30A01A1. Création : 16/11/1999.