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  1. Universal hepatitis B immunization : infant, and infant plus adolescent immunization.

    Article, Communication - En anglais

    VHPB International Congress. Madrid, ESP, 1997/11/17.

    Hepatitis B virus (HBV) is one of the world's most widespread infectious agents and the cause of millions of diseases and deaths each year.

    Vaccination programmes aimed at risk groups are important for individual protection, but will not eliminate viral transmission in Europe, since 70% of acute hepatitis B cases are either acquired by sexual activity or are of unknown origin.

    In industrialized countries.

    HBV infection occurs mainly in young adults, however, when the virus is acquired during infancy it leads to extremely high rates of chronic carriership, contributing disproportionately to the overall pool of HBsAg carriers.

    This explains why integrating universal HB vaccination into routine infant immunization programmes is the best means for controlling HB in countries with intermediate to high levels of HB endemicity.

    In countries of low endemicity, universal immunization of adolescents may be considered as an alternative to infant vaccination, as this strategy has a more rapid effect on the epidemiology of the infection.

    Where feasible, a double strategy (infant plus adolescent) is the optimal solution.

    With this strategy, adolescent immunization is necessary only for the time required for the first cohort of immunized infants to reach adolescence. (...)

    Mots-clés Pascal : Virus hépatite B, Orthohepadnavirus, Hepadnaviridae, Virus, Nourrisson, Homme, Adolescent, Epidémiologie, Prévalence, Facteur risque, Programme sanitaire, Vaccination, Hépatite virale B, Virose, Infection, Appareil digestif pathologie, Foie pathologie, Article synthèse

    Mots-clés Pascal anglais : Hepatitis B virus, Orthohepadnavirus, Hepadnaviridae, Virus, Infant, Human, Adolescent, Epidemiology, Prevalence, Risk factor, Sanitary program, Vaccination, Viral hepatitis B, Viral disease, Infection, Digestive diseases, Hepatic disease, Review

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0146301

    Code Inist : 002B05A02. Création : 16/11/1999.