Hepatitis B and blood safety.
VHPB International Congress. Madrid, ESP, 1997/11/17.
The safety of blood and blood products is a global issue.
Blood transfusion is an important part of modern medicine, but it is also an efficient route of transmission for a number of infectious agents.
Although many countries screen all blood donations for a number of infectious agents, a significant proportion of the world's blood supply is either unscreened or poorly screened, with the resultant risk to recipients of transfusion transmitted infections (TTI).
Hepatitis B virus (HBV) is of concern because it is transmitted parenterally, many HBV infections are asymptomatic (and infected individuals may thus unwittingly present as blood donors) and the virus is stable in blood and blood products over long periods.
The transmission of HBV is minimized by the screening of donors prior to donation, exclusion of high-risk donors, followed by the in-vitro screening of donations for HBsAg (-anti-HBc in some countries) prior to transfusion.
However, even in countries with good quality, active screening programmes, there is still a small residual risk of transmission of HBV from undetected donors with early acute infection. resolving infection, silent infection or infection with atypical virus serology.
Unfortunately, as with so many infectious agents, the prevalence of HBV is most often higher in those countries with poorly developed healthcare systems and limited resources. (...)
Mots-clés Pascal : Virus hépatite B, Orthohepadnavirus, Hepadnaviridae, Virus, Homme, Donneur sang, Dépistage, Transmission homme homme, Prévention, Facteur risque, Hépatite virale B, Virose, Infection, Appareil digestif pathologie, Foie pathologie, Article synthèse
Mots-clés Pascal anglais : Hepatitis B virus, Orthohepadnavirus, Hepadnaviridae, Virus, Human, Blood donor, Medical screening, Transmission from man to man, Prevention, Risk factor, Viral hepatitis B, Viral disease, Infection, Digestive diseases, Hepatic disease, Review
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0145734
Code Inist : 002B27D01. Création : 16/11/1999.