The incidence of collagenous and lymphocytic colitis is not well known.
We sought to assess the incidence of collagenous and lymphocytic colitis in a well-defined population during a 5-yr study period.
From January 1,1993, to December 31,1997, all new patients diagnosed with collagenous or lymphocytic colitis living in the catchment area of the Hospital Mútua de Terrassa (Barcelona, Spain) were identified.
Since 1993 all patients with chronic diarrhea were referred for a diagnostic colonoscopy.
Multiple biopsy sampling of the entire colon was performed when appearance of the colonic mucosa was grossly normal.
Twenty-three cases of collagenous colitis and 37 of lymphocytic colitis were diagnosed.
The female : male ratios were 4.75 : 1 and 2.7 : 1 for collagenous and lymphocytic colitis, respectively.
The mean age at onset of symptoms was 53.4 ± 3.2 (range, 29-82) yr for collagenous colitis, and 64.3 ± 2.7 (range, 28-87) yr for lymphocytic colitis (p=0.012).
The mean annual incidence per 100,000 inhabitants based on the year of onset of symptoms was 1.1 (95% confidence interval [CI], 0.4-1.7) for collagenous colitis, and 3.1 (95% CI, 2.0-4.2) for lymphocytic colitis.
A peak incidence was observed in older women in both diseases.
A rate of microscopic colitis of 9.5 per 100 normal-looking colonoscopies performed in patients with chronic watery diarrhea was observed. (...)
Mots-clés Pascal : Colite collagène, Lymphocytose, Incidence, Diarrhée, Symptomatologie, Indication, Colonoscopie, Diagnostic, Epidémiologie, Homme, Appareil digestif pathologie, Intestin pathologie, Endoscopie
Mots-clés Pascal anglais : Collagenous colitis, Lymphocytosis, Incidence, Diarrhea, Symptomatology, Indication, Colonoscopy, Diagnosis, Epidemiology, Human, Digestive diseases, Intestinal disease, Endoscopy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0141312
Code Inist : 002B13B03. Création : 16/11/1999.