INTERNAL MEDICINE, vol. 37, n° 11, 1998, pages 913-916, 32 réf., ISSN 0918-2918, JPN
MIYASHITA (N.), TOYOTA (E.), SAWAYAMA (T.), MATSUMOTO (A.), MIKAMI (Y.), KAWAI (N.), TAKADA (K.), NIKI (Y.), MATSUSHIMA (T.)
Division of Respiratory Diseases. Kawasaki Medical School. Kurashiki. JPN, Division of Cardiology. Department of Medicine. Kawasaki Medical School. Kurashiki. JPN, Department of Cardiology. Seikeikai Hospital. Osaka. JPN
The association of Chlamydia pneumoniae with atherosclerosis of coronary and carotid arteries and the aorta has been demonstrated by seroepidemiology and by detection of the organism in atheromata.
We investigated the frequency of C. pneumoniae seropositivity in patients with acute myocardial infarction (AMI).
C. pneumoniae-specific antibodies were measured by the microimmunofluorescence test in 160 AM patients and 160 control subjects matched for age and gender.
The odds ratios (ORs) were 2.2 (95% confidence interval (CI), 1.2 to 3.9) for immunoglobulin (Ig) G and 2.7 (95% CI, 1.7 to 4.3) for IgA.
After adjustment for other cardiovascular risk factors of age, gender, hypertension, diabetes, cigarette smoking and serum cholesterol, the ORs were essentially unchanged.
This study confirmed that the observations of an association between antibody against C. pneumoniae and coronary heart disease in Western nations is also present in Japan.
Our results are comparable to the previous seroepidemiological studies reporting ORs of 2.0 or greater.
Mots-clés BDSP : Bactérie, Bactériose, Infection, Infarctus, Myocarde, Cardiopathie coronaire, Artériosclérose, Epidémiologie, Facteur risque, Prévalence, Homme, Japon, Asie, Appareil circulatoire [pathologie], Myocarde [pathologie], Vaisseau sanguin [pathologie]
Mots-clés Pascal : Chlamydia pneumoniae, Chlamydiaceae, Chlamydiales, Bactérie, Bactériose, Infection, Chronique, Infarctus, Myocarde, Cardiopathie coronaire, Athérosclérose, Carotide, Epidémiologie, Facteur risque, Prévalence, Homme, Japon, Asie, Appareil circulatoire pathologie, Myocarde pathologie, Vaisseau sanguin pathologie, Artère pathologie
Mots-clés Pascal anglais : Chlamydia pneumoniae, Chlamydiaceae, Chlamydiales, Bacteria, Bacteriosis, Infection, Chronic, Infarct, Myocardium, Coronary heart disease, Atherosclerosis, Carotid, Epidemiology, Risk factor, Prevalence, Human, Japan, Asia, Cardiovascular disease, Myocardial disease, Vascular disease, Arterial disease
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Cote : 99-0136835
Code Inist : 002B12A03. Création : 16/11/1999.