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  1. Prevalence of the metabolic syndrome in drug-treated hypertensive patients and control subjects.

    Article - En anglais

    Objectives

    To determine the prevalence of the metabolic abnormalities associated with hypertension and to define the predictors of the metabolic syndrome by different definitions in random population-based samples.

    Design

    A cross-sectional epidemiological study of hypertensive patients and controls.

    Setting

    The participating study subjects visited the research laboratory of the Department of Internal Medicine.

    University of Oulu, Oulu.

    Finland.

    Subjects

    Six hundred treated male and female hypertensives aged 40-59 years and 600 age-and sex-matched controls were randomly selected by age stratification from population registers.

    Main outcome measures

    A wide range of laboratory analyses were conducted.

    After fasting blood had been drawn, the subjects were given a 75 g glucose load except previously known insulin-treated diabetics.

    Both 1 h and h h glucose and insulin concentrations were determined.

    During the same visit, a standardized health questionnaire covering the past medical history, current and former medication use. physical activity, smoking habits, alcohol consumption and family history was completed.

    Ten different definitions of the metabolic syndrome were applied to achieve a wide perspective of the prevalence of the different combinations.

    Results

    The prevalence of the metabolic syndrome in different samples varied depending on the definition from 0.8 to 35.3%, being lowest in the control men and women and highest in the hypertensive men. (...)

    Mots-clés Pascal : Hypertension artérielle, Prévalence, Homme, Métabolisme, Exploration, Glucose, Epidémiologie, Finlande, Europe, Lipide, X Syndrome, Facteur risque, Athérosclérose, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Hypertension, Prevalence, Human, Metabolism, Exploration, Glucose, Epidemiology, Finland, Europe, Lipids, X Syndrome, Risk factor, Atherosclerosis, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0131249

    Code Inist : 002B12B05B. Création : 16/11/1999.