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  1. Gains in life expectancy after elimination of major causes of death : revised estimates taking into account the effect of competing causes.

    Article - En anglais

    Background-It is generally acknowledged that conventional estimates of the potential number of life years to be gained by elimination of causes of death are too generous.

    This is because these estimates fail to take into account the fact that those who are saved from the cause are likely to have one or more other conditions ( « competing » causes of death), which may increase their risks of dying.

    It is unknown to what extent this introduces bias in comparisons of life years to be gained between underlying causes of death.

    The purpose of the study was to assess this bias.

    Data and methods-A sample of 5975 death certificates from the Netherlands, 1990, was coded for the presence of diseases that, according to a set of explicit rules, could be regarded as potential causes of death « competing » with the underlying cause.

    Logistic regression analysis was used to quantify age and sex adjusted differences between four main underlying causes of death (neoplasms, cardiovascular diseases, respiratory diseases, all other diseases) in prevalence of the six most frequent competing causes of death (neoplasms, ischaemic heart disease, cerebrovascular disease, other cardiovascular diseases, chronic obstructive lung disease, all other diseases).

    These prevalence differences were then used to revise conventional calculations of gains in life expectancy, by taking them to indicate differences in risk of dying from these competing causes after the underlying cause has been eliminated. (...)

    Mots-clés Pascal : Pays Bas, Europe, Evaluation, Homme, Mortalité, Certificat décès, Analyse statistique, Régression statistique, Age, Sexe, Classification, Cause, Source information, Espérance vie

    Mots-clés Pascal anglais : Netherlands, Europe, Evaluation, Human, Mortality, Death certificate, Statistical analysis, Statistical regression, Age, Sex, Classification, Cause, Information source

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0127684

    Code Inist : 002B30A01C. Création : 16/11/1999.