The aim of this study was to evaluate the influence on preterm delivery of changes in putative genetic and environmental risk factors between two consecutive births.
Low social status is a suspected risk indicator of preterm delivery, but the impact of social mobility has not been studied before.
Participants-The study uses national cohorts in which women act as their own controls.
Subjects were identified by means of registries : 10 455 women who gave birth to a preterm child and had a subsequent live birth between 1980 and 1992 and 9849 women who gave birth to a child after 37 completed weeks of gestation and had a subsequent live born child in the same time period formed the cohorts.
Methods-The risk of having a premature infant in the subsequent pregnancy was analysed in each cohort as a function of changes in male partner, residency, occupation, and social status between the two pregnancies.
There was a strong tendency to repeat a preterm delivery (18% v 6% in the general population).
Social decline was associated with a moderate increase in the recurrence risk (OR : 1.22 ; 95% CI : 1.02,1.47).
In the reference cohort the risk of preterm delivery associated with changing from a rural to an urban municipality was 2.03 (95% CI : 1.14,3.64).
Conclusions-Social decline and moving to an urban municipality may be associated with preterm delivery.
Mots-clés Pascal : Homme, Femelle, Danemark, Europe, Epidémiologie, Récidive, Facteur risque, Etude cohorte, Statut socioéconomique, Mobilité sociale, Prématurité, Statut social, Père
Mots-clés Pascal anglais : Human, Female, Denmark, Europe, Epidemiology, Relapse, Risk factor, Cohort study, Socioeconomic status, Social mobility, Prematurity, Social status, Father
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0127682
Code Inist : 002B20F02. Création : 16/11/1999.