The possible modifying effect of social relations on the association between depression and mortality was examined in a community-based cohort study.
A total of 3,777 randomly selected persons 65 years of age and older in southwest France were followed over a 5-year period from 1988 in the Personnes Agées Quid (PAQUID).
At study entry, the prevalence of elevated depressive symptomatology was 12.9% for men and 14.7% for women, and the reported relative isolation was 14.1% for men and 26.0% for women.
During a total of 16,984 person-years of follow-up, 849 deaths occurred.
Among participants with high levels of depressive symptomatology, the age-adjusted mortality rate ratio was 2.10 (95% confidence interval 1.7-2.7) in men and 1.76 (95% confidence interval 1.4-2.3) in women.
When compared with individuals with the most connections, men and women with few social network connections were also at increased risk of mortality : age-adjusted rate ratio=2.69 (95% confidence interval 1.9-3.8) for men and 1.56 (95% confidence interval 1.0-2.4) for women.
Satisfaction with social support had a small but nonsignificant effect on mortality risk.
For women, the excess risks due to depressive symptoms and few network connections are observed only in the 65-to 74-year age group, after adjusting for health and health behaviors. (...)
Mots-clés Pascal : Etat dépressif, Personne âgée, Homme, Sexe, Etude cohorte, Mortalité, Epidémiologie, France, Europe, Support social, Trouble humeur
Mots-clés Pascal anglais : Depression, Elderly, Human, Sex, Cohort study, Mortality, Epidemiology, France, Europe, Social support, Mood disorder
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0127236
Code Inist : 002B18E. Création : 16/11/1999.