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  1. Should African-American men be tested for prostate carcinoma at an earlier age than white men ?

    Article, Communication - En anglais

    Annual meeting of the American Urological Association. New Orleans, LA, USA, 1997/04.


    There have recently been challenges to testing high risk populations, i.e., African-American men younger than 50 years, for prostate carcinoma (PCa).

    The mortality rate of patients with PCa between ages 40 and 60 years is nearly 3 times greater among African-American men (AAM) compared with white men (WM).

    The literature in support of testing AAM at an earlier age than WM is sparse.

    Therefore, the authors present clinical and histologic data that support the testing of AAM at a younger age, utilizing data on patients with clinically localized PCa.


    Examination of consecutive radical prostatectomy specimens from AAM and WM was performed from January 1991 to June 1996 among AAM and WM at Wayne State University, Harper Hospital, Detroit, Michigan.

    International, salvage prostatectomy, and neoadjuvant hormonal therapy patients were excluded, as were patients with lymph node metastasis.

    The authors examined biochemical recurrences of PCa in this cohort of men treated from January 1991 through December 1995.

    Univariate analysis of contingency tables was performed, using chi-squared-tests to assess the correlation between stage and race after stratification of patients by age group.

    Biochemical recurrence was analyzed using the Kaplan-Meier method and the log rank test.


    The authors examined radical prostatectomy specimens from 759 patients and biochemical recurrence outcome of 655 patients. (...)

    Mots-clés Pascal : Carcinome, Prostate, Dépistage, Age, Noir américain, Ethnie, Race, Pronostic, Etats Unis, Amérique du Nord, Amérique, Homme, Tumeur maligne, Prostate pathologie, Appareil urinaire pathologie, Appareil génital mâle pathologie

    Mots-clés Pascal anglais : Carcinoma, Prostate, Medical screening, Age, Black American, Ethnic group, Race, Prognosis, United States, North America, America, Human, Malignant tumor, Prostate disease, Urinary system disease, Male genital diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0120478

    Code Inist : 002B14D02. Création : 16/11/1999.