Sunlight and non-Hodgkin's lymphoma : A population-based cohort study in Sweden.
Indirect evidence, notably ecological comparisons and an association with skin cancer, links non-Hodgkin's lymphoma (NHL) with exposure to sunlight.
We conducted a population-based, nationwide cohort study with exposure to outdoor work inferred from job titles reported in the population and housing censuses in 1960 andlor 1970 and by classifying each individual's work and home addresses according to latitude.
Follow-up for cancer incidence was accomplished through record linkages with the virtually complete Swedish Cancer Registry.
The cohort included all Swedish residents who were recorded as gainfully employed in both censuses.
Altogether 4,171,175 individuals contributing 69,639,237 person-years accrued through 1989 were included in the analyses.
We identified 10,381 cases of NHL, 4,018 cases of chronic lymphocytic leukemia (CLL), 11,398 cases of malignant melanoma (MM) and 11,913 cases of squamous cell skin cancer (SCC).
We calculated age-adjusted relative risks for NHL, CLL, MM and SCC in strata based on estimated residential and occupational sunlight exposure.
Interaction effects were considered for pesticide and solvent exposure.
NHL, MM and SCC, but not CLL, were positively associated with increasingly southerly residential latitude, with stronger associations seen for skin cancer compared to NHL.
Occupational sun exposure was not associated with the risk of developing any of the studied cancers. (...)
Mots-clés Pascal : Lymphome non hodgkinien, Facteur risque, Incidence, Epidémiologie, Rayonnement solaire, Rayonnement UV, Onde électromagnétique, Pesticide, Solvant, Exposition professionnelle, Zone résidentielle, Suède, Europe, Registre, Etude cohorte, Homme, Hémopathie maligne, Lymphoprolifératif syndrome
Mots-clés Pascal anglais : Non Hodgkin lymphoma, Risk factor, Incidence, Epidemiology, Solar radiation, Ultraviolet radiation, Electromagnetic wave, Pesticides, Solvent, Occupational exposure, Residential zone, Sweden, Europe, Register, Cohort study, Human, Malignant hemopathy, Lymphoproliferative syndrome
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0120436
Code Inist : 002B19B. Création : 16/11/1999.