California, the leading agricultural state in the United States, has maintained a population-based cancer registry since 1988, and it also maintains a comprehensive, state-wide pesticide reporting system.
Data on cancer incidence and pesticide use reporting are available, by county, for all 58 counties in California.
Average annual age-adjusted cancer incidence rates (1988-1992), on a county-sex-and race/ethnicity-specific basis, were obtained from the California Cancer Registry (CCR), which maintains the population-based cancer registry throughout California.
Pesticide use data (i.e., pounds of active ingredient applied annually in each county) were obtained from the California Department of Pesticide Regulation for 1993.
Investigators used Pearson product-moment correlation coefficients (r) to correlate age-adjusted incidence rates for selected cancers with the use data for selected pesticides.
For most sex-and race/ethnicity-specific groups, the correlation coefficients were very close to zero or negative in sign, indicating no correlation between pesticide use and cancer incidence.
There were, however, several exceptions, particularly in Hispanic males for whom the following correlations were observed : leukemia and atrazine (r=40), leukemia and 2,4-dichlorophenoxyacetic acid (r=41), leukemia and captan (r=46), atrazine and brain cancer (r=54), and atrazine and testicular cancer (r=41). (...)
Mots-clés Pascal : Pesticide, Toxicité, Epidémiologie, Homme, Tumeur maligne, Californie, Etats Unis, Amérique du Nord, Amérique, Age, Sexe, Ethnie
Mots-clés Pascal anglais : Pesticides, Toxicity, Epidemiology, Human, Malignant tumor, California, United States, North America, America, Age, Sex, Ethnic group
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0116429
Code Inist : 002B03G. Création : 16/11/1999.