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  1. Epidemiology of emerging pneumococcal drug resistance : implications for treatment and prevention.

    Article - En anglais

    Drug-resistant Streptococcus pneumoniae infection are becoming increasingly common throughout the world.

    These strains pose new challenges in the treatment of suspected pneumococcal infections, and they highlight the importance of limiting selection for resistant strains through judicious antibiotic use and preventing infection by immunization of persons at high risk.

    The clinical impact of drug-resistant S. pneumoniae infection has not been fully defined, but anecdotal reports suggest that outcome is poor for persons with drug-resistant pneumococcal meningitis.

    The American Academy of Pediatrics has recommended adding vancomycin to the treatment of suspected pneumococcal meningitis cases until the results of culture and susceptibility testing are available.

    Additional data are needed to determine the optimal empiric antibiotic regimen for nonmeningeal invasive pneumococcal imfections.

    A 23-valent pneumococcal capsular polysaccharide vaccine can prevent many drug-resistant and susceptible invasive pneumococcal infections.

    The vaccine is recommended in the United States for persons at increased risk of pneumococcal infeaction due to certain medical conditions and for all persons >=65 years old.

    Vaccine efficacy for immunocompetent persons>65 years is 75%. (...)

    Mots-clés Pascal : Streptococcus pneumoniae, Streptococcaceae, Micrococcales, Bactérie, Homme, Pneumococcie, Streptococcie, Bactériose, Infection, Epidémiologie, Résistance, Traitement, Chimiothérapie, Antibactérien, Antibiotique, Vaccin, Prévention, Article synthèse, Méningite, Pneumonie, Système nerveux pathologie, Système nerveux central pathologie, Appareil respiratoire pathologie, Poumon pathologie

    Mots-clés Pascal anglais : Streptococcus pneumoniae, Streptococcaceae, Micrococcales, Bacteria, Human, Pneumococcal infection, Streptococcal infection, Bacteriosis, Infection, Epidemiology, Resistance, Treatment, Chemotherapy, Antibacterial agent, Antibiotic, Vaccine, Prevention, Review, Meningitis, Pneumonia, Nervous system diseases, Central nervous system disease, Respiratory disease, Lung disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0114086

    Code Inist : 002A05B11. Création : 16/11/1999.