Factors contributing to mortality in burned children with acute renal failure have been identified ; however, they have not been identified in thermally injured adults.
The records of 1,404 acutely burned adults admitted to the Blocker Burn Unit were reviewed.
Seventy-six patients with acute renal dysfunction and burns covering more than 30% of their total body surface area with a full-thickness component greater than 10% total body surface area were identified.
These patients were divided into those admitted from 1981 through 1989 (n=35) and those admitted from 1990 to 1998 (n=41).
No significant differences could be shown in the incidence of acute renal dysfunction (5.4 vs. 5.1%) or mortality (88 vs. 87%) for the two time periods, respectively.
Sixty-seven percent of the survivors were younger than 40 years of age, compared with only 25% of nonsurvivors (p<0.02) ; sepsis was identified in 44 and 96% of survivors and nonsurvivors, respectively (p<0.001).
Fluid resuscitation was delayed in survivors by 1.7 ± 1.0 hours compared with 4.4 ± 2.1 hours in nonsurvivors (p<0.001).
Early fluid resuscitation and the prevention of sepsis may reduce the incidence of acute renal dysfunction and mortality in burned adults.
Mots-clés Pascal : Brûlure, Indice gravité, Adulte, Homme, Insuffisance rénale, Aigu, Complication, Epidémiologie, Incidence, Facteur risque, Mortalité, Traitement, Traumatisme, Appareil urinaire pathologie, Rein pathologie
Mots-clés Pascal anglais : Burn, Severity score, Adult, Human, Renal failure, Acute, Complication, Epidemiology, Incidence, Risk factor, Mortality, Treatment, Trauma, Urinary system disease, Kidney disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0113593
Code Inist : 002B16J. Création : 16/11/1999.