Osteoporosis is a common condition, which is recognised by the occurrence of fragility fractures and leads to considerable mortality and morbidity with huge financial implications world-wide.
Based on predicted demographic changes, the implications of this disease are set to increasingly affect the healthcare budgets of all nations.
The determinants of fracture are skeletal factors, such as peak bone mass, the rate of bone loss and extra-skeletal factors, which include trauma and the response to that trauma.
Some of these factors are genetically determined, but several have environmental origins, which could, theoretically, be manipulated.
There are two potential means whereby osteoporotic fractures might be prevented.
Measures could be targeted at the entire population, with the aim of shifting the distribution of bone mass in a beneficial direction, through modifying the behaviour of all individuals.
The alternative is a high risk approach, whereby intervention is targeted only at those considered to have the greatest risk of future fracture.
Mass bone density screening falls into the second approach.
Bone density is a good predictor of future fracture risk, and cost-effectiveness analyses of the high risk approach suggest economic benefits of policies targeting pharmacological treatment to those individuals at highest risk. (...)
Mots-clés Pascal : Ostéoporose, Dépistage, Politique sanitaire, Fracture, Os, Prévention, Complication, Analyse avantage coût, Homme, Système ostéoarticulaire pathologie, Ostéopathie, Traumatisme
Mots-clés Pascal anglais : Osteoporosis, Medical screening, Health policy, Fracture, Bone, Prevention, Complication, Cost benefit analysis, Human, Diseases of the osteoarticular system, Bone disease, Trauma
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0110087
Code Inist : 002B15A. Création : 16/11/1999.