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  1. Helicobacter pylori infection in children with celiac disease : Prevalence and clinicopathologic features.

    Article - En anglais


    Celiac disease is frequently associated with chronic gastritis.

    Helicobacter pylori is the main etiologic agent of chronic gastritis.

    The aim of this study was to assess the prevalence of H. pylori, the related symptoms, and the endoscopic and histologic gastric features in children with celiac disease.


    Eight-one (24 boys. 57 girls ; age range : 1.4-17.7 years, median 6.8) children with celiac disease were studied.

    All children had a blood sample taken.

    In a subgroup of 30 children who underwent endoscopy, three gastric biopsy specimens were taken for histology (hematoxylin and eosin, Giemsa, immunohistochemistry) and urease quick test.

    Symptom complaints were recorded.

    Age-and sex-matched (one case, one control) children without celiac disease were used for comparison.

    Serum H. pylori IgG were measured by means of a locally validated commercial enzyme-linked immunoassay.


    Overall, 15 of 81 (18.5%) children with celiac disease and 14 of 81 (17.3%) control children were positive for H. pylori.

    The percentage of H. pylori positivity was similar in children with untreated and treated celiac disease.

    Recurrent abdominal pain was the only symptom that helped to distinguish between H. pylori-positive and H. pylori-negative children.

    However, symptoms disappeared in patients with celiac disease after gluten withdrawal, irrespective of H. pylori status. (...)

    Mots-clés Pascal : Coeliaque maladie, Complication, Gastrite, Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, Prévalence, Symptomatologie, Histopathologie, Gastroscopie, Epidémiologie, Enfant, Homme, Appareil digestif pathologie, Intestin pathologie, Malabsorption intestinale, Immunopathologie, Estomac pathologie, Endoscopie

    Mots-clés Pascal anglais : Coeliac disease, Complication, Gastritis, Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, Prevalence, Symptomatology, Histopathology, Gastroscopy, Epidemiology, Child, Human, Digestive diseases, Intestinal disease, Intestinal malabsorption, Immunopathology, Gastric disease, Endoscopy

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0109580

    Code Inist : 002B13B03. Création : 16/11/1999.