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  1. Historical cohort study of a New Zealand foundry and heavy engineering plant.

    Article - En anglais

    Objectives-To investigate the mortality of workers who had been exposed to asbestos, machining fluids and foundry work in a foundry and heavy engineering plant in the railway rolling stock manufacturing industry in New Zealand.

    Methods-Historical cohort study design

    Results

    For the total workforce of 3522 men employed between 1945 and 1991, follow up was 90% of person-years to 31 December 1991.

    Significantly increased standardised mortality ratios (SMRs) were found for all causes of death combined (SMR 1.07 ; 95% confidence interval (95% CI) 1.01 to 1.14), all malignancies (SMR 1.15 ; 95% CI 1.01 to 1.31), circulatory (SMR 1.16 ; 95% CI 1.07 to 1.27) and musculoskeletal diseases (SMR 3.06 ; 95% CI 1.39 to 5.84), all digestive cancers (SMR 1.29 ; 95% CI 1.04 to 1.59), all respiratory cancers (SMR 1.34 ; 95% CI 1.08 to 1.65), cancer of the oesophagus (SMR 1.97 ; 95% CI 1.01 to 3.45), and mesothelioma of the pleura (SMR 6.58 ; 95% CI 1.24 to 19.49).

    Three deaths from pleural mesothelioma were recorded, with latency times of 51,53, and 57 years.

    There were no dose-response relations between exposure to asbestos, machining fluids or foundry work, or by duration of employment in the plant, and any cause of death.

    Conclusions-This study found small increases in risk for several causes of death among foundry and heavy engineering workers ; however, these increases were small and the possible effects of smoking and other lifestyle factors could not be excluded. (...)

    Mots-clés Pascal : Exposition professionnelle, Médecine travail, Amiante, Industrie fonderie, Huile minérale, Homme, Mortalité, Etude cohorte, Recherche rétrospective, Epidémiologie, Nouvelle Zélande, Océanie, Etiologie, Facteur risque

    Mots-clés Pascal anglais : Occupational exposure, Occupational medicine, Asbestos, Foundry industry, Mineral oil, Human, Mortality, Cohort study, Retrospective searching, Epidemiology, New Zealand, Oceania, Etiology, Risk factor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0109001

    Code Inist : 002B03L03. Création : 16/11/1999.