Objectives-It is plausible that neurodegenerative processes of aging might have a contributing role in the development of chronic effects of exposure to organic solvents.
This study evaluated the risk for neuropsychological deficits among retired workers, relative to their histories of exposure to occupational solvents.
Methods-This cross sectional study evaluated retired male workers, 62-74 years of age, including 89 people with previous long term occupational exposure to solvents (67 retired painters and 22 retired aerospace manufacturing workers), and 126 retired carpenters with relatively minimal previous exposure to solvents.
Subjects completed a standardised neuropsychological evaluation and psychiatric interview, structured interviews for histories of occupational exposure and alcohol consumption, and questionnaires assessing neurological and depressive symptoms.
By comparison with the carpenters, the painters on average reported greater cumulative alcohol consumption and had lower scores on the WAIS-R vocabulary subtest, usually presumed to reflect premorbid intellectual functioning.
These findings, however, were not sufficient to account for the other study findings. (...)
Mots-clés Pascal : Exposition professionnelle, Médecine travail, Solvant organique, Trouble neurologique, Industrie, Retraite, Personne âgée, Homme, Etude cas témoin, Questionnaire, Psychométrie, Neuropsychologie, Analyse statistique, Toxicité, Symptomatologie, Evaluation, Système nerveux pathologie, Histoire professionnelle
Mots-clés Pascal anglais : Occupational exposure, Occupational medicine, Organic solvent, Neurological disorder, Industry, Retirement, Elderly, Human, Case control study, Questionnaire, Psychometrics, Neuropsychologia, Statistical analysis, Toxicity, Symptomatology, Evaluation, Nervous system diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0108996
Code Inist : 002B03L04. Création : 16/11/1999.