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  1. Day treatment versus enhanced standard methadone services for opioid-dependent patients : A comparison of clinical efficacy and cost.

    Article - En anglais


    This study examined the differential efficacy and relative costs of two intensities of adjunctive psychosocial services-a day treatment program and enhanced standard care-for the treatment of opioid-dependent patients maintained on methadone hydrochloride.


    A 12-week randomized clinical trial with 6-month follow-up was conducted in a community-based methadone maintenance program.

    Of the 308 patients who met inclusion criteria, 291 began treatment (day treatment program : N=145 ; enhanced standard care : N=146), and 237 completed treatment (82% of those assigned to the day treatment program and 81% of those receiving enhanced standard care).

    Two hundred twenty of the patients participated in the 6-month follow-up (75% of those in the day treatment program and 73% of those in enhanced standard care provided a follow-up urine sample for screening).

    Both interventions were 12 weeks in duration, manual-guided, and provided by master's-level clinicians.

    The day treatment was an intensive, 25-hour-per-week program.

    The enhanced standard care was standard methadone maintenance plus a weekly skills training group and referral to on-and off-site services.

    Outcome measures included twice weekly urine toxicology screens, severity of addiction-related problems, prevalence of HIV risk behaviors, and program costs. (...)

    Mots-clés Pascal : Dépendance, Opiacés, Toxicomanie, Sevrage toxique, Traitement, Hôpital jour, Etude comparative, Chimiothérapie, Méthadone, Analgésique narcotique, Traitement substitutif, Efficacité traitement, Analyse coût, Economie santé, Santé mentale, Homme

    Mots-clés Pascal anglais : Dependence, Opiates, Drug addiction, Detoxification, Treatment, Day hospital, Comparative study, Chemotherapy, Methadone, Narcotic analgesic, Replacement therapy, Treatment efficiency, Cost analysis, Health economy, Mental health, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0105698

    Code Inist : 002B18I15. Création : 16/11/1999.