Background Physicians use myocardial perfusion imaging to a variable extent in patients presenting with possible coronary artery disease.
There are few clinical data on the most cost-effective strategy although computer models predict that routine use of myocardial perfusion imaging is cost-effective.
Objectives To measure the cost-effectiveness of four diagnostic strategies in patients newly presenting with possible coronary artery disease, and to compare cost-effectiveness in centres that routinely use myocardial perfusion imaging with those that do not.
Methods We have studied 396 paticnts presenting to eight hospitals for the diagnosis of coronary artery disease.
The hospitals were regular users or non-users of myocardial perfusion imaging with one of each in four countries (France.
Germany, Italy, United Kingdom).
Information was gathered retrospectively on presentation, investigations, complications, and clinical management, and patients were followed-up for 2 years in order to assess outcome.
Pre-and post-test probabilities of coronary artery disease were computed for diagnostic tests and cach test was also assigned as diagnostic or part of management.
Diagnostic strategies defined were : I : Exercise electrocardiogram/coronary angiography. 2 : exercise electrocardiogram/myocardial perfusion imaging/coronary angiography. 3 : myocardial perfusion imaging/coronary angiography. 4 : coronary angiography. (...)
Mots-clés Pascal : Cardiopathie coronaire, Scintigraphie, Perfusion, Myocarde, Analyse coût efficacité, Economie santé, Diagnostic, Homme, Appareil circulatoire pathologie, Exploration radioisotopique, Imagerie médicale
Mots-clés Pascal anglais : Coronary heart disease, Scintigraphy, Perfusion, Myocardium, Cost efficiency analysis, Health economy, Diagnosis, Human, Cardiovascular disease, Radionuclide study, Medical imagery
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0104226
Code Inist : 002B12A03. Création : 16/11/1999.