The epidemiology of cognitive decline over 11.5 years was investigated in a large community-residing population, with a special emphasis on the relationship between education and cognitive decline.
The study was an 11.5-year follow-up of a probability sample of the adult household residents of east Baltimore.
From the Baltimore cohort of the Epidemiologic Catchment Area study, 1,488 participants completed the Mini-Mental State during three study waves in 1981,1982, and 1993-1996.
For each study participant, the difference in scores on the Mini-Mental State between waves 2 and 3 was calculated.
Over a median interval of 11.5 years, the study participants'scores on the Mini-Mental State declined a mean of 1.41 points, and the scores of 68% of the participants declined by at least 1 Mini-Mental State point.
With and without adjustment for age, greater declines were associated with having 8 years or less of formal education and with being African American.
Over a long time period, cognitive decline occurred in all age groups.
Having more than 8 years of formal education was associated with less decline.
However, beyond 9 years, additional education was not associated with a further reduction in cognitive decline.
This suggests that a minimal amount of education during early critical periods might confer protection against cognitive decline later in life.
Mots-clés Pascal : Trouble cognition, Détérioration intellectuelle, Etude longitudinale, Long terme, Maryland, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Santé mentale, Adulte, Homme
Mots-clés Pascal anglais : Cognitive disorder, Intellectual deterioration, Follow up study, Long term, Maryland, United States, North America, America, Epidemiology, Mental health, Adult, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0103924
Code Inist : 002B18C14. Création : 16/11/1999.