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  1. Cognitive decline in adulthood : An 11.5-year follow-up of the Baltimore Epidemiologic Catchment Area study.

    Article - En anglais


    The epidemiology of cognitive decline over 11.5 years was investigated in a large community-residing population, with a special emphasis on the relationship between education and cognitive decline.


    The study was an 11.5-year follow-up of a probability sample of the adult household residents of east Baltimore.

    From the Baltimore cohort of the Epidemiologic Catchment Area study, 1,488 participants completed the Mini-Mental State during three study waves in 1981,1982, and 1993-1996.

    For each study participant, the difference in scores on the Mini-Mental State between waves 2 and 3 was calculated.


    Over a median interval of 11.5 years, the study participants'scores on the Mini-Mental State declined a mean of 1.41 points, and the scores of 68% of the participants declined by at least 1 Mini-Mental State point.

    With and without adjustment for age, greater declines were associated with having 8 years or less of formal education and with being African American.


    Over a long time period, cognitive decline occurred in all age groups.

    Having more than 8 years of formal education was associated with less decline.

    However, beyond 9 years, additional education was not associated with a further reduction in cognitive decline.

    This suggests that a minimal amount of education during early critical periods might confer protection against cognitive decline later in life.

    Mots-clés Pascal : Trouble cognition, Détérioration intellectuelle, Etude longitudinale, Long terme, Maryland, Etats Unis, Amérique du Nord, Amérique, Epidémiologie, Santé mentale, Adulte, Homme

    Mots-clés Pascal anglais : Cognitive disorder, Intellectual deterioration, Follow up study, Long term, Maryland, United States, North America, America, Epidemiology, Mental health, Adult, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0103924

    Code Inist : 002B18C14. Création : 16/11/1999.