To determine the frequency of pericardial and pleural effusions in scleroderma.
Using a case-control format, patients with scleroderma and no known cardiac disease were recruited.
Echocardiograms and chest radiographs were performed.
Age-and gender-matched controls had echocardiograms performed which were read by a cardiologist, blinded to the diagnosis.
The medical records of 60 other scleroderma patients were also reviewed.
Thirty-seven scleroderma subjects were recruited, of whom 18 had diffuse disease.
Only eight subjects with diffuse disease and five with limited scleroderma had normal echocardiograms compared to 20 of 37 controls (P<0.1).
Two had pericardial effusions, both with diffuse scleroderma, and none of the controls had effusions present.
Pulmonary hypertension occurred in three with diffuse disease and no controls.
A chart review of a further 60 patients with scleroderma was performed.
Pleural effusions were identified in 7% (4/58) of the cohort of scleroderma patients and were more frequent in diffuse disease (10%). A total of 17% (4/23) of diffuse and 4% (1/23) of limited scleroderma patients had evidence of pericardial effusions.
Pericardial effusions do occur in scleroderma without evidence of clinical cardiac dysfunction and are more common in diffuse scleroderma.
Pleural effusions in scleroderma occur less frequently, in 7%.
Mots-clés Pascal : Sclérodermie, Complication, Homme, Epanchement, Péricarde, Symptomatologie, Plèvre, Exploration, Epidémiologie, Fréquence, Radiographie, Echocardiographie, Peau pathologie, Tissu conjonctif pathologie, Maladie système, Maladie autoimmune, Immunopathologie, Appareil circulatoire pathologie, Cardiopathie, Péricarde pathologie, Appareil respiratoire pathologie, Plèvre pathologie, Exploration ultrason
Mots-clés Pascal anglais : Scleroderma, Complication, Human, Effusion, Pericardium, Symptomatology, Pleura, Exploration, Epidemiology, Frequency, Radiography, Echocardiography, Skin disease, Connective tissue disease, Systemic disease, Autoimmune disease, Immunopathology, Cardiovascular disease, Heart disease, Pericardial disease, Respiratory disease, Pleural disease, Sonography
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0091653
Code Inist : 002B07. Création : 31/05/1999.