Objective To study the relationship between human immunodeficiency virus (HIV) infection and body weight in African women during and after pregnancy.
Methods A prospective cohort study was initiated at the Centre Hospitalier de Kigali in July 1992.
Every woman seen at the antenatal clinic and with a gestational age of<28 weeks was offered HIV-1 antibody testing.
Comparable numbers of HIV-infected (HIV+) and uninfected (HIV-) women were recruited.
At inclusion, socio-demographic characteristics and self-reported pre-pregnancy weight were recorded ; height and weight were measured.
Each woman enrolled had a monthly follow-up until 9 months after delivery, with a clinical examination including weighing.
Three anthropometric indices were used to answer the study objectives : weight, body mass index (BMI), and pregnancy balance.
Results As of April 1994,101 HIV+and 106 HIV-women were followed until 5 months after delivery.
Weight and BMI during pregnancy were lower in HIV+women than in HIV-women.
After delivery, weight and BMI gains were significantly lower in HIV+women.
Until 5 months after delivery, the mean weight variation was - 2.2 kg (standard deviation [SD]=5.9 kg) in HIV+women and+0.2 kg (SD=6.6 kg) in HIV-women (P=0.007) in comparison to pre-pregnancy weight.
Comparisons of the slopes of the weight curves did not show statistical differences throughout the pregnancy, but it did during the post-partum period (P=0.02). (...)
Mots-clés Pascal : SIDA, Virose, Infection, Gestation, Postpartum, Poids corporel, Modification, Epidémiologie, Facteur risque, Homme, Femelle, Rwanda, Afrique, Immunopathologie, Immunodéficit, Biométrie corporelle
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Pregnancy, Puerperium, Body weight, Modification, Epidemiology, Risk factor, Human, Female, Rwanda, Africa, Immunopathology, Immune deficiency, Corporal biometry
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0086935
Code Inist : 002B05C02D. Création : 31/05/1999.