logo BDSP

Base documentaire


  1. Screening for congenital heart malformation in child health centres.

    Article - En anglais

    Background Although screening for congenital heart malformations is part of the child health care programme in several countries, there are very few published evaluations of these activities.

    This report is concerned with the evaluation of this screening at the Dutch Child Health Centres (CHC).

    Methods All consecutive patients, aged between 32 days and 4 years, presented at the Sophia Children's Hospital Rotterdam throughout a period of 2 years, with a congenital heart malformation were included in this study.

    Paediatric cardiologists established whether or not these patients were diagnosed after haemodynamic complications had already developed (diagnosed'too late'). Parents and CHC-physicians were interviewed in order to establish the screening and detection history.

    Test properties were established for all patients with a congenital heart malformation (n=290), intended effects of screening were established in patients with clinically significant malformations (n=82).

    Results The sensitivity of the actual screening programme was 0.57 (95% Cl : 0.51-0.62), the specificity 0.985 (95% CI : 0.981-0.990) and the predictive value of a positive test result 0.13 (95% CI : 0.10-0.19).

    Sensitivity in a subpopulation of patients adequately screened was 0.89 (95% CI : 0.74-0.96).

    Adequately screened patients were less likely to be diagnosed'too late'than inadequately screened patients (odds ratio [OR]=0.20,95% CI : 0.04-1.05). (...)

    Mots-clés Pascal : Cardiopathie, Congénital, Programme sanitaire, Epidémiologie, Diagnostic, Dépistage, Evaluation, Enfant, Homme, Pays Bas, Europe, Appareil circulatoire pathologie, Maladie congénitale

    Mots-clés Pascal anglais : Heart disease, Congenital, Sanitary program, Epidemiology, Diagnosis, Medical screening, Evaluation, Child, Human, Netherlands, Europe, Cardiovascular disease, Congenital disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0086927

    Code Inist : 002B12A08. Création : 31/05/1999.