Background Depressed respiratory function and respiratory symptoms are associated with impaired survival.
The present study was undertaken to assess the relation between respiratory symptoms and mortality from cardiovascular causes, cancer and all causes in a large population of middle-aged men.
Methods Prospective population study of 6442 men aged 51-59 at baseline, free of clinical angina pectoris and prior myocardial infarction.
Results During 16 years there were 1804 deaths (786 from cardiovascular disease, 608 from cancer, 103 from pulmonary disease and 307 from any other cause).
Men with effort-related breathlessness had increased risk of dying from all of the examined diseases.
After adjustment for age, smoking habit and other risk factors, the relative risk (RR) associated with breathlessness of dying from coronary disease was 1.43 (95% Cl : 1.16-1.77), from stroke 1.77 (95% Cl : 1.07-2.93), from any cardiovascular disease 1.48 (95% Cl : 1.24-1.76), cancer 1.36 (95% Cl : 1.11-1.67) and from any cause 1.62 (95% Cl : 1.44-1.81).
An independent effect of breathlessness on cardiovascular death, cancer death and mortality from all causes was found in life-time non-smokers, and also if men with chest pain not considered to be angina were excluded.
An independent effect was also found if all deaths during the first half of the follow-up were excluded. (...)
Mots-clés Pascal : Mortalité, Appareil respiratoire pathologie, Cardiopathie coronaire, Appareil circulatoire pathologie, Tumeur maligne, Epidémiologie, Taux, Facteur risque, Homme, Mâle, Suède, Europe
Mots-clés Pascal anglais : Mortality, Respiratory disease, Coronary heart disease, Cardiovascular disease, Malignant tumor, Epidemiology, Rate, Risk factor, Human, Male, Sweden, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0086923
Code Inist : 002B30A01A2. Création : 31/05/1999.