Persistence of susceptibility to measles in france despite routine immunization : A cohort analysis.
This study examined the impact of French routine programs urging the combined measles-mumps-rubella immunization of 15-month-old children.
We applied a cohort analysis to surveillance data collected by general practitioners to estimate the cumulative incidence rate per 1000 unvaccinated children and the proportion of susceptible chilldren, by age and for each birth cohort between 1985 and 1995.
More than 70% of unvaccinated children born in 1985 and 1986 had measles by the age of 10.
This incidence rate dramatically decreased after implementation of the routine measles-mumps-rubella immunization program in 1989, but the proportion of 5-year-olds susceptible to measles has not decreased appreciably.
In 1996, more than 15% of the chlldren born between 1990 and 1995 were susceptible.
The measles vaccine coverage achieved by the French routine immunization program remains insufficient as regards reducing the number of susceptible children.
Mots-clés Pascal : Rougeole, Virose, Infection, Nourrisson, Homme, France, Europe, Prévention, Vaccination, Programme sanitaire, Etude cohorte, Etude statistique, Immunoprotection
Mots-clés Pascal anglais : Measles, Viral disease, Infection, Infant, Human, France, Europe, Prevention, Vaccination, Sanitary program, Cohort study, Statistical study, Immunoprotection
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0082799
Code Inist : 002B05C02B. Création : 31/05/1999.