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  1. Fulltext. Previous lung disease and risk of lung cancer among men and women nonsmokers.

    Article - En anglais


    From 1982 to 1984, the authors conducted a population-based case-control study of lung cancer in men and women nonsmokers in New York State.

    In-person interviews were completed for 437 lung cancer cases (197 never smokers, 240 former smokers) and 437 matched population controls.

    Cases and controls were asked to report any history of physician-diagnosed nonmalignant lung disease ; cases were more likely than controls to report such a history.

    Statistically significant associations were found for emphysema (odds ratio (OR)=1.94,95% confidence interval (Cl) 1.10-3.43), chronic bronchitis (OR=1.73,95% CI 1.10-2.72), and the combined endpoint of emphysema, chronic bronchitis, or asthma (OR=1.82,95% CI 1.26-2.63).

    After adjustment for active and passive tobacco smoke exposure, emphysema, chronic bronchitis, and asthma (each condition and the combined endpoint) were significantly associated with lung cancer risk.

    The risk was more marked for squamous cell carcinomas and for subjects who were diagnosed at older ages, and it remained significant when surrogate interviews were excluded.

    These results are consistent with the hypothesis that certain prior lung conditions increase the risk of lung cancer in men and women nonsmokers.

    Mots-clés Pascal : Tumeur maligne, Bronchopulmonaire, Homme, Facteur risque, Pneumopathie, Bronchite, Asthme, Emphysème, Epidémiologie, Sexe, Facteur sociodémographique, New York, Etats Unis, Amérique du Nord, Amérique, Appareil respiratoire pathologie, Poumon pathologie, Bronche pathologie, Bronchopneumopathie obstructive

    Mots-clés Pascal anglais : Malignant tumor, Bronchopulmonary, Human, Risk factor, Pneumopathy, Bronchitis, Asthma, Emphysema, Epidemiology, Sex, Sociodemographic factor, New York, United States, North America, America, Respiratory disease, Lung disease, Bronchus disease, Obstructive pulmonary disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0082028

    Code Inist : 002B11A. Création : 31/05/1999.