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  1. Angina pectoris in a contemporary population : Characteristics and therapeutic implications.

    Article, Communication - En anglais

    Management of Ischemic Heart Disease : Therapeutic Options and Future Directions - Satellite Symposium. .

    We characterized a contemporary, nonhospitalized population with angina pectoris by obtaining data from a geographically diverse cohort of 5125 outpatients with chronic stable angina cared for by 1266 primary-care physicians.

    Diagnosis was based on history supported by evidence for coronary artery disease (coronary angiography, old myocardial infarction [MI], and/or an abnormal stress test).

    Their mean age was 69 years and 53% were women.

    Seventy percent had more than one associated illness, and 65% used more than one cardiovascular drug.

    Calcium antagonists (46%) and nitrates (61%) were used most frequently.

    Median angina frequency was approximately 2 episodes/week, and increased angina frequency was associated (P<0.0001) with decreased overall feeling of well-being.

    Although effort angina was present in 90% of patients, 47% also had rest angina and 34% had mental stress-evoked angina.

    Female gender (odds ratio : 1.09 ; 95% CI : 1.02-1.16), concomitant illness (1.17,1.09-1.25), and pharmacotherapy (1.14,1.07-1.22) were associated with rest angina.

    Younger age (1.30,1.20-1.41), female gender (1.16,1.07-1.26), concomitant illness (1.13,1.03-1.24), and pharmacotherapy (1.28,1.15-1.93) were associated with mental stress angina.

    Calcium antagonists were used for rest-evoked (1.09,1.03-1.16) and mental stress-evoked (1.12,1.04-1.21) angina. (...)

    Mots-clés Pascal : Homme, Traitement, Chimiothérapie, Ambulatoire, Etude cohorte, Infarctus, Myocarde, Artère coronaire, Diagnostic, Epidémiologie, Physiopathologie, Sexe, Comparaison interindividuelle, Prévalence, Mâle, Femelle, Age, Personne âgée, Appareil circulatoire pathologie, Cardiopathie coronaire, Myocarde pathologie

    Mots-clés Pascal anglais : Human, Treatment, Chemotherapy, Ambulatory, Cohort study, Infarct, Myocardium, Coronary artery, Diagnosis, Epidemiology, Pathophysiology, Sex, Interindividual comparison, Prevalence, Male, Female, Age, Elderly, Cardiovascular disease, Coronary heart disease, Myocardial disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 99-0079546

    Code Inist : 002B12A03. Création : 31/05/1999.