Objective To determine annual incidence and prevalence for patients consulting their GP because of Crohn's disease in England and Wales and compare demographic details with matched controls.
Design We used the fourth Morbidity Statistics in General Practice study (MSGP-4) which covered 468 042 person-years during a 12-month period in 1991-92.
Methods All GPs reporting a patient with Crohn's disease in MSGP-4 were sent a questionnaire to confirm the diagnosis and obtain supportive details (surgical, pathological, radiological and/or endoscopic).
Data concerning ethnicity, social class, smoking status, living in an urban or rural environment and employment had been collected previously.
Conditional logistic regression models were used to analyse the data for cases and matched controls.
Results Three hundred and fifteen patients were reported to have Crohn's disease.
Replies were obtained to 251 (80%) questionnaires.
The diagnosis of Crohn's disease was confirmed in 184 cases (89%) and refuted in 23 cases (11%) - details were unavailable for 44 patients.
The mean age of patients was 44 years, the female : male ratio was 1.46 : 1, and 108 (59%) patients had required surgery.
Thirty-three of 178 (18.5%) patients were diagnosed within the study period.
Hence, this study detected a prevalence for consulting Crohn's disease of 54.6-59.8/100 000 and an annual incidence of 10.1-11.1/100,000 in 1991-92. (...)
Mots-clés Pascal : Entérite Crohn, Incidence, Prévalence, Facteur risque, Questionnaire, Epidémiologie, Homme, Grande Bretagne, Royaume Uni, Europe, Appareil digestif pathologie, Intestin pathologie, Maladie inflammatoire
Mots-clés Pascal anglais : Crohn disease, Incidence, Prevalence, Risk factor, Questionnaire, Epidemiology, Human, Great Britain, United Kingdom, Europe, Digestive diseases, Intestinal disease, Inflammatory disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0074733
Code Inist : 002B13B03. Création : 31/05/1999.