Context. - The Lifestyle Heart Trial demonstrated that intensive lifestyle changes may lead to regression of coronary atherosclerosis after 1 year.
- To determine the feasibility of patients to sustain intensive lifestyle changes for a total of 5 years and the effects of these lifestyle changes (without lipid-lowering drugs) on coronary heart disease.
- Randomized controlled trial conducted from 1986 to 1992 using a randomized invitational design.
- Forty-eight patients with moderate to severe coronary heart disease were randomized to an intensive lifestyle change group or to a usual-care control group, and 35 completed the 5-year follow-up quantitative coronary arteriography.
- Two tertiary care university medical centers.
- lntensive lifestyle changes (10% fat whole foods vegetarian diet, aerobic exercise, stress management training, smoking cessation, group psychosocial support) for 5 years.
- Adherence to intensive lifestyle changes, changes in coronary artery percent diameter stenosis, and cardiac events.
- Experimental group patients (20 [71% ] of 28 patients completed 5-year follow-up) made and maintained comprehensive lifestyle changes for 5 years, whereas control group patients (15 [75% ] of 20 patients completed 5-year follow-up) made more moderate changes.
In the experimental group, the average percent diameter stenosis at baseline decreased 1. (...)
Mots-clés Pascal : Cardiopathie coronaire, Facteur risque, Réversibilité, Athérosclérose, Changement comportement, Effet milieu, Comportement alimentaire, Etude statistique, Randomisation, Etude comparative, Mode de vie, Adulte, Homme, Appareil circulatoire pathologie, Vaisseau sanguin pathologie
Mots-clés Pascal anglais : Coronary heart disease, Risk factor, Reversibility, Atherosclerosis, Behavior change, Medium effect, Feeding behavior, Statistical study, Randomization, Comparative study, Life style, Adult, Human, Cardiovascular disease, Vascular disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 99-0070835
Code Inist : 002B12A03. Création : 31/05/1999.